Chains of Mephistopheles + Dredger's Insight + Golgari Thug + Marina Vendrell's Grimoire

Prerequisites

• You have a way to draw a card.

Steps

1. 1Attempt to draw a card.
2. 2The draw will be replaced by Chains of Mephistopheles, instead causing you to discard Golgari Thug. Then, the draw will be replaced by Golgari Thug's dredge ability, causing you to mill cards and return Golgari Thug from your graveyard to your hand.
3. 3Dredger's Insight's first ability triggers, causing you to gain 1 life.
4. 4Marina Vendrell's Grimoire triggers, attempting to draw a card.
5. 5Repeat from step 2.

Effects

• Infinite self-mill
• Near-infinite lifegain
• Near-infinite lifegain triggers
• Near-infinite self-discard triggers