Chains of Mephistopheles + Dredger's Insight + Lich's Mastery + Necroplasm

Prerequisites

• You have a way to draw a card.

Steps

1. 1Attempt to draw a card.
2. 2The draw will be replaced by Chains of Mephistopheles, instead causing you to discard Necroplasm. Then, the draw will be replaced by Necroplasm's dredge ability, causing you to mill cards and return Necroplasm from your graveyard to your hand.
3. 3Dredger's Insight's first ability triggers, causing you to gain 1 life.
4. 4Lich's Mastery triggers, attempting to draw a card.
5. 5Repeat from step 2.

Effects

• Infinite self-mill
• Near-infinite lifegain
• Near-infinite lifegain triggers
• Near-infinite self-discard triggers