Malcolm, Keen-Eyed Navigator + Niv-Mizzet, the Firemind + Quicksmith Genius + Amoeboid Changeling

Prerequisites

• You have a way to draw a card.
• Amoeboid Changeling does not have summoning sickness.

Steps

1. 1Activate Amoeboid Changeling's first ability by tapping it, causing Niv-Mizzet to gain all creature types until end of turn.
2. 2Draw a card.
3. 3Niv-Mizzet triggers, dealing 1 damage to an opponent.
4. 4Malcom triggers, creating a Treasure token.
5. 5When the Treasure enters the battlefield, Quicksmith Genius triggers, causing you to loot.
6. 6Repeat from step 3.

Effects

• Infinite draw triggers
• Infinite looting
• Infinite self-discard triggers
• Near-infinite colored mana
• Near-infinite damage
• Near-infinite Treasure tokens